High Purity Prilocaine Powders Local Anesthetic Drugs 721-50-6
Prilocaine Quick detail
Product Name: Prilocaine
Prilocaine CAS: 721-50-6
Prilocaine MF: C13H20N2O
Prilocaine MW: 220.31
Prilocaine EINECS: 211-957-0
Prilocaine Categories: Active Pharmaceutical Ingredients
Prilocaine Chemical properties : acicular crystallization. The
melting point of 37-38 degrees, 159-162 degrees (0.133kPa) of
boiling point, refractive index (nD20) 1.5299. The hydrochloride
([1786-81-8]) is a white crystalline powder. Temperature 167-168
degrees. Soluble in water and ethanol, slightly soluble in
chloroform. Sour bitter taste, no smell.
Usage : Pharmaceutical Intermediates .
Prilocaine is a local anesthetic of the amino amide type .it is
often used in dentistry. It is also often
combined with lidocaine as a topical preparation for dermal
anesthesia (lidocaine/prilocaine or EMLA), for
treatment of conditions like paresthesia. As it has low cardiac
toxicity, it is commonly used for intravenous
regional anaesthesia (IVRA).
In some patients, ortho-toluidine, a metabolite of prilocaine, may
cause methemoglobinemia, which may betreated with methylene blue.
Prilocaine may also be contraindicated in people with sickle cell
anemia, or symptomatic hypoxia.
Main applications are as follows:The material for Local anesthetic.
White or almost white crystalline powder
Freely soluble in water and in alcohol
99.0--101.0% (calculated on the dried basis)
Loss on Drying
Not more than 0.3%
Not more than 1.0%
Not more than 5000ppm
Not more than 5000ppm
Not more than 0.15%
Not more than 0.001%
Proparacaine hydrochloride and tetracaine are also indicated to
produce local anesthesia prior to surgical procedures such as
cataract extraction and pterygium excision, usually as an adjunct
to locally injected anesthetics.
Ophthalmic solutions used for intraocular procedures should be
preservative-free. Preservatives may cause damage to the corneal
epithelium if a significant quantity of solutionenters the eye
through the incision.
Prilocaine topical may also be used for other purposes not listed
in this medication guide.
For a variety of surgical epidural block and infiltration
Prilocaine topical is a local anesthetic (numbing medication).It
works by blocking nerve signals in your body.Prilocaine topical is
used to numb the skin, or surfaces of the penis or vagina, in
preparation for a medical procedure or to lessen the pain of
inserting a medical instrument such as a tube or speculum.
Local anesthetic is a substance that causes loss of sensation only
to the area to which it is applied without affecting consciousness.
Most local anesthetics structures have amino-ester or an
amino-amide group which are linked to hydrophilic (secondary or
tertiary amine) and to hydrophobic group (aromatics) on the other
Local anesthetics, long duration, lower toxicity, chemicals that
are also small Suitable for epidural anesthesia, block anesthesia
and infiltration anesthesia, etc.
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Q1: Are you a manufacturer?
A: Yes, We manufacture bulk products in our factory located in
Jiayu, Hubei, and produce small quantity and customer synthesis
products in our lab located in Wuhan.
Q2: Do you have stock?
A: We understand most customers prefer stock, so we'll try to keep
stock for most products. However, for some rare products, we won't
keep stock and it needs time to synthesize.
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A: Some technical paperwork is available, such as COA, HNMR, HPLC,
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